| Autor: |
Jorge, Ortiz-González, Nora Patricia, Alvarez-Aguila, Juan Manuel, Medina-Castro |
| Rok vydání: |
2005 |
| Předmět: |
|
| Zdroj: |
Anticancer research. 25(5) |
| ISSN: |
0250-7005 |
| Popis: |
The serum level of carbohydrate antigen 19-9 (CA 19-9) depends on the tumor size and differentiation grade. Jaundice can cause an elevation of serum CA 19-9, although the nature of this interaction is not fully understood.This was a retrospective study of 26 patients with potentially resectable pancreatic adenocarcinoma. Serum CA 19-9 was correlated with the histological differentiation. CA 19-9 adjusted for serum bilirubin was determined and analyzed.No correlation between CA 19-9 and histological differentiation was determined (p0.05). The median adjusted CA 19-9 level was significantly lower (p=0.01) in patients with normal biliary excretion than those with bilirubin levels2 mg/dL.These data are consonant with the theory of a dual contribution to the serum CA 19-9 level from biliary obstruction and tumor cell synthesis. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
