Chronic nicotine ingestion improves radial arm maze performance in rats

Autor: S., Poincheval-Fuhrman, S.J., Sara
Rok vydání: 1993
Zdroj: Behavioural pharmacology. 4(5)
ISSN: 1473-5849
Popis: Effects of chronic nicotine treatment on spatial memory were studied in rats. After 3 weeks of administration of 2.5mg/kg/day in drinking water, the rats were submitted to a spatial learning task in an eight-arm radial maze, during which time the treatment was maintained. Chronic nicotine treatment improved daily spatial memory performance after the animals reached an asymptotic level. Nicotine-treated animals showed significantly better performance than control animals regarding the first error and the total correct path choices.
Databáze: OpenAIRE