111In-pentetreotide in the study of tumors expressing somatostatin receptors
| Autor: | J, Mateos Fernández, F, Pons Pons, D, Fuster Pelfort, S, Vidal-Sicart, F, Lomeña Caballero, R, Herranz García-Romero |
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| Rok vydání: | 1999 |
| Předmět: |
Adult
Male Adrenal Gland Neoplasms Glucagonoma Carcinoid Tumor Pheochromocytoma Sensitivity and Specificity Biomarkers Tumor Humans Receptors Somatostatin Thyroid Neoplasms Radionuclide Imaging Aged Indium Radioisotopes Liver Neoplasms Middle Aged Neoplasm Proteins Pancreatic Neoplasms Neuroendocrine Tumors Evaluation Studies as Topic Carcinoma Medullary Gastrinoma Female Insulinoma Radiopharmaceuticals Somatostatin Tomography X-Ray Computed |
| Zdroj: | Revista espanola de medicina nuclear. 18(5) |
| ISSN: | 0212-6982 |
| Popis: | The usefulness of 111In-pentetreotide scintigraphy in the diagnosis of neuroendocrine tumors was evaluated.39 patients with clinical or biochemical suspicion of neuroendocrine tumors were studied. 29 patients underwent surgery and diagnosis was confirmed by anatomopathology findings (7 mixed tumors, 6 carcinoids, 3 insulinomas, 3 pheocromocytomas, 2 glucagonomas, 2 medullary thyroid carcinomas, 1 gastrinoma and 5 metastatic lesions). In 10 patients who did not undergo surgery, the diagnostic criteria were based on a 6 month follow-up. 111In-pentetreotide scintigraphy and computed tomography (CT) were performed in all of the patients.The scintigraphy correctly detected 58% of the primary tumors while the CT was positive in only 45% of the cases. Both techniques detected metastasis in 5 patients.111In-pentetreotide scintigraphy is a useful technique to diagnose those tumors that have somatostatin receptors. In our series, the sensitivity of this method was higher than the CT. |
| Databáze: | OpenAIRE |
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