| Autor: |
S, Ishiura, N, Sasagawa, N, Saitoh, H, Koike, H, Sorimachi, K, Suzuki, M, Shimokawa, F, Usuki, H, Nakase, K, Kamakura |
| Rok vydání: |
1995 |
| Předmět: |
|
| Zdroj: |
Rinsho shinkeigaku = Clinical neurology. 35(12) |
| ISSN: |
0009-918X |
| Popis: |
The mutation underlying myotonic dystrophy is the expansion of polymorphic CTG repeat in the 3'-noncoding region of the myotonin protein kinase (MtPK) gene mapping to chromosome 19q13.3. A full-length cDNA of human MtPK was cloned and expressed in COS-1 cells. MtPK is recovered from the COS cell extract as a 70 kDa protein, which coincides with the size deduced from the predicted amino acid sequence. Biochemical characteristics of MtPK expressed in COS cells and its expression are investigated. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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