Antiplaque and antigingivitis effectiveness of a hexetidine mouthwash

Autor: N C, Sharma, H J, Galustians, J, Qaqish, C H, Charles, J W, Vincent, J A, McGuire
Rok vydání: 2003
Předmět:
Zdroj: Journal of clinical periodontology. 30(7)
ISSN: 0303-6979
Popis: To assess the antiplaque/antigingivitis efficacy of a hexetidine-containing mouthwash.This examiner-blind, parallel group, controlled clinical study examined the effectiveness of a hexetidine (0.1%) mouthwash both in inhibiting the development of supragingival plaque and in reducing gingivitis. One hundred and thirty-four adult subjects completed the 2-week experimental gingivitis model study. Following baseline examinations, which included plaque index, modified gingival index and gingival bleeding index, subjects received a full dental prophylaxis. Subjects were randomly assigned to one of three mouthwashes (hexetidine 0.1%, chlorhexidine 0.12% (positive control) or a 5% hydroalcohol negative control) and commenced three times daily supervised rinsing as their sole method of oral hygiene. All indices were rescored after 2 weeks.Compared to the negative control group, the hexetidine group demonstrated a statistically significant inhibition and reduction of supragingival plaque and gingival inflammation with reductions of 6.3%, 33.5% and 56% for gingivitis, plaque and gingival bleeding, respectively. The results of the chlorhexidine group were used to validate the study.The study confirms the efficacy of a hexetidine rinse in reducing supragingival plaque and gingival inflammation.
Databáze: OpenAIRE