[A new method of a morphometric study of the kidney using a computer-assisted morphometric complex 'Diamorph']

Autor: A V, Zhukotskiĭ, N I, Iakubova, A B, Ponomarev, B A, Purtov, M A, Pal'tsev, E M, Kogan
Rok vydání: 1992
Předmět:
Zdroj: Biulleten' eksperimental'noi biologii i meditsiny. 113(4)
ISSN: 0365-9615
Popis: The use of a computer--based morphometric complex "DIAMORPH" for automated morphometric analysis of renal glomeruli is described. By combining the principles of morphological and functional approaches to diagnosis with the capabilities of present--day research equipment, a new informative morphometric parameter--the extent of capillary--mesangium contact--has been identified. With this parameter and its derivatives, it has been possible to differentiate, in a statistically significant way (p less than 0.01), healthy subjects (controls) from patients with manifest diabetes mellitus of up to I year in duration who could not be distinguished through light microscopic or conventional morphometric studies.
Databáze: OpenAIRE