[Papular acantholytic dyskeratosis]

Autor: H L, de Almeida Júnior, M, Wolter, L A, Castro, N E, Rocha
Jazyk: němčina
Rok vydání: 2002
Předmět:
Zdroj: Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete. 52(12)
ISSN: 0017-8470
Popis: Papular acantholytic dyskeratosis is a very rare skin disease, which shows a suprabasilar cleft with acantholytic and dyskeratotic cells, simulating the light microscopic picture of Darier disease. In this condition, the lesions are acquired without a genetic basis. We observed a 40-year-old woman with about 200 papules on the lower aspects of her legs; histological examination showed changes similar to Darier disease. Transmission electron microscopy showed a reduced number of desmosomes and perinuclear distribution of tonofilaments. The lesions were successfully treated with cryotherapy with spray technique.
Databáze: OpenAIRE