Clinical Inquiries: What are the benefits and risks of daily low-dose aspirin for primary prevention of CV events?

Autor: Justin, Mutter, Rebecca, Grandy, Stephen, Hulkower, Sue, Stigleman
Rok vydání: 2018
Předmět:
Zdroj: The Journal of family practice. 67(4)
ISSN: 1533-7294
Popis: One nonfatal myocardial infarction (MI) will be avoided for every 126 to 138 adults who take daily aspirin for 10 years (strength of recommendation [SOR]: A, systematic reviews and meta-analyses of multiple randomized controlled trials [RCTs]). Taking low-dose aspirin for primary prevention shows no clear mortality benefit. A benefit for primary prevention of stroke is less certain. Although no evidence establishes increased risk of hemorrhagic stroke from daily low-dose aspirin, one gastrointestinal hemorrhage will occur for every 72 to 357 adults who take aspirin for longer than 10 years (SOR: A, systematic reviews and meta-analyses of multiple RCTs and cohort studies).
Databáze: OpenAIRE