Triple combination antimicrobial regimen in the treatment of infections of neutropenic cancer patients

Autor: A, Casali, S, Santini, M, Della Giulia, L, Di Lauro, P, Vici, T, Gionfra, F M, Sega
Rok vydání: 1997
Předmět:
Zdroj: Journal of experimentalclinical cancer research : CR. 16(3)
ISSN: 0392-9078
Popis: Twenty-six cancer patients (pts) with chemotherapy-related neutropenic fever were treated with vancomycin 30 mg/m2/day i.v. every 12 hrs, imipenem 1500 mg/day i.v. every 8 hrs, and pefloxacin 800 mg/day i.v. every 12 hrs. Twelve fevers of unknown origin (FUO), 10 gram-positive, 3 gram-negative and 1 mycoplasma were also treated. Globally, cure was observed in 22 pts (84%) and failure in 4 pts (16%); in gram-positive infections alone, cure was observed in 10 pts (80%) and failure in 4 pts (20%). Defervescence was obtained within 3 days in 77% pts. No relevant side effects were observed.
Databáze: OpenAIRE