| Autor: |
Ru-Gen, Wan, De-Bao, Chen, Yong-Gang, Lou, Mao-Feng, Wang, Qiao-Hong, Zhang, Dan-Xia, Jin, Sun-Hong, Zhou |
| Rok vydání: |
2011 |
| Předmět: |
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| Zdroj: |
Zhonghua zhong liu za zhi [Chinese journal of oncology]. 33(1) |
| ISSN: |
0253-3766 |
| Popis: |
To evaluate the diagnostic value of serum angiopoietin-2 (Ang-2) level in pancreatic cancer patients.Serum Ang-2 level was measured by enzyme-linked immunosorbent assays (ELISA) in samples from 116 patients with pancreatic cancer, 50 patients with chronic pancreatitis, and 50 normal control subjects.The serum Ang-2 level in patients with pancreatic cancer [(1539.0 ± 449.3) ng/L] was significantly higher than those in patients with pancreatitis [(1044.6 ± 246.1) ng/L, P0.01] and normal control subjects [(1075.6 ± 228.2) ng/L, P0.01]. There was no significant difference of serum Ang-2 levels between patients with pancreatitis and normal controls. Pancreatic caner patients with lymph node metastasis had a significantly higher serum Ang-2 level [(1890.1 ± 354.9) ng/L] than those without metastasis [(1212.1 ± 224.2) ng/L, P0.01]. The area under ROC curve of serum Ang-2 level for diagnosis of pancreatic cancer was 0.819.The serum Ang-2 level can be a useful indicator for diagnosis of pancreatic cancer. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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