[Molecular-biological and antigenic features of H5N1 subtype highly pathogenic influenza virus strains isolated in southern Siberia in 2005-2009]

Autor: K A, Sharshov, A G, Durymanov, A A, Romanovskaia, A V, Zaĭkovskaia, V Iu, Marchenko, N Iu, Silko, F A, Il'inykh, I M, Susloparov, A Iu, Alekseev, A M, Shestopalov
Rok vydání: 2011
Předmět:
Zdroj: Zhurnal mikrobiologii, epidemiologii i immunobiologii. (5)
ISSN: 0372-9311
Popis: Study of molecular-biological and antigenic features of H5N1 subtype virus strains isolated in southern Siberia in 2005-2009.Study was performed by using standard procedures according to WHO recommendations.Hemagglutinin gene of H5N1 subtype virus strain isolated in Siberia belongs to 2 genetical lineages: 2.2 and 2.3.2. Strains of these 2 lineages have antigenic differences. All of the strains are highly pathogenic for chicken and white mice.H5N1 subtype highly pathogenic influenza virus variants of 2 different antigenic lineages that have antigenic differences circulated in Siberia in 2005-2009. A possible role of antigenic drift in evolution of H5N1 subtype influenza virus is discussed.
Databáze: OpenAIRE