The effects of exercise duration on adrenal HSP72/73 induction in rats

Autor:	H A, Demirel, S K, Powers, H, Naito, N, Tumer
Rok vydání:	1999
Předmět:	Time Factors Blotting Western Body Weight HSC70 Heat-Shock Proteins HSP72 Heat-Shock Proteins Organ Size Adaptation Physiological Rats Rats Sprague-Dawley Physical Conditioning Animal Adrenal Glands Animals Female HSP70 Heat-Shock Proteins Carrier Proteins Heat-Shock Proteins
Zdroj:	Acta physiologica Scandinavica. 167(3)
ISSN:	0001-6772
Popis:	This study investigated the effects of varying durations of exercise training on heat shock proteins 72 and 73 (HSP72/73) induction in the rat adrenal gland. Female Sprague-Dawley rats (120 days old) were assigned to either a sedentary control group (C) or one of the three endurance exercise training groups. Trained animals ran on a treadmill at approximately 75% VO2max for 10 weeks (4-5 days week-1) at one of the three different exercise durations (30 min day-1=T30, 60 min day-1=T60, or 90 min day-1=T90). All durations of exercise training resulted in an increase in the HSP72 levels (P0.0001). The magnitude of the training-induced elevation in the HSP72 levels in the adrenal gland increased as a function of the training duration ( approximately 60-fold increase in T90; approximately 40-fold increase in T60; and approximately 15-fold increase in T30). Longer exercise durations (60 min day-1), also resulted in small but significant increase in HSP73 level ( approximately 1.2-fold increase in both T60 and T90; P0.05). These results demonstrate that the physiological stress created by chronic treadmill running can induce both HSP72 and HSP73 in rat adrenal gland. Increased levels of adrenal HSP72/73 expression during rigorous exercise, may be one of the adaptive mechanisms of the adrenals to cope with an increased dose of stress.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::cf1968c2227575295d5563524d7be9d3 https://pubmed.ncbi.nlm.nih.gov/10606824 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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