[Action of antioxidants on membrane-toxic effects of anticholinesterase agents]

Autor: E P, Zatsepin, N N, Churaev, T A, Uspenskaia, G D, Tirzit, G Ia, Dubur
Rok vydání: 1990
Předmět:
Zdroj: Biulleten' eksperimental'noi biologii i meditsiny. 110(12)
ISSN: 0365-9615
Popis: It was found therapeutic-preventive effectiveness of antioxidants (1,4-dihydropyridine derivatives) at poisoning with malathion insecticide. The effect of 1,4-dihydropyridine derivatives can be attributed to a prevention of lipid peroxidation. Antioxidants do not affect the toxicity of 0,0-dimethyl-0-2,2-dichlorvinylphosphate. Thus, antioxidants are pathogenetic drugs for treatment of poisonings with cholinesterase inhibitors.
Databáze: OpenAIRE