Faithful mRNA splicing depends on the Prp19 complex subunit

Autor: Julia, Sauerwald, Charlotte, Soneson, Mark D, Robinson, Stefan, Luschnig
Rok vydání: 2016
Předmět:
Zdroj: Development (Cambridge, England). 144(4)
ISSN: 1477-9129
Popis: Morphogenesis requires the dynamic regulation of gene expression, including transcription, mRNA maturation and translation. Dysfunction of the general mRNA splicing machinery can cause surprisingly specific cellular phenotypes, but the basis for these effects is not clear. Here, we show that the
Databáze: OpenAIRE