Glycosaminoglycans in the synovial fluids of patients with juvenile rheumatoid arthritis

Autor: P F, Spelling, N, Heise, O M, Toledo
Rok vydání: 1991
Předmět:
Zdroj: Clinical and experimental rheumatology. 9(2)
ISSN: 0392-856X
Popis: A simple method was used to isolate hyaluronic acid (HA) and sulfated glycosaminoglycans from synovial fluids obtained from children with juvenile rheumatoid arthritis (JRA) and from normal age-matched controls. The bulk of the glycosaminoglycans present in both normal and pathologic synovial fluids consisted of hyaluronic acid and chondroitin 6-sulfate. The diseased synovial fluids showed a sharp decrease in the concentration of glycosaminoglycans when compared with normal controls. These findings are similar to those reported for the synovial fluid of adult patients with rheumatoid arthritis.
Databáze: OpenAIRE