| Autor: |
O P, Vakulina, V V, Iasnetsov, V A, Isachenkov, I N, Krylova, I P, Tishkova, E O, Bragin, E V, Popkova |
| Rok vydání: |
1990 |
| Předmět: |
|
| Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny. 109(2) |
| ISSN: |
0365-9615 |
| Popis: |
It has been shown, that piracetam by i.p. injection (10, 100, 400 mg/kg) or by consumption with drinking water 10, 100, 1000 mg/kg/day during 12 days delays extinction of conditioned reflex of passive avoidance and dose-dependence elevates exploratory activity in "open field", pain sensitivity threshold reduces to 70-75%. Prolonged consumption of 1000 mg/kg/day piracetam results in 3-fold decrease of beta-endorphin concentration in plasma (p less than 0.01) and 100 mg/kg/day--in 35% increase of cAMP content in rat brain cortex. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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