| Autor: |
Janina, Auth, Maria, Fröba, Maximilian, Große, Pia, Rauch, Natalia, Ruetalo, Michael, Schindler, Martina, Morokutti-Kurz, Philipp, Graf, Andrea, Dolischka, Eva, Prieschl-Grassauer, Christian, Setz, Ulrich, Schubert |
| Rok vydání: |
2021 |
| Předmět: |
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| Zdroj: |
International Journal of Molecular Sciences |
| ISSN: |
1422-0067 |
| Popis: |
Even in the face of global vaccination campaigns, there is still an urgent need for effective antivirals against SARS-CoV-2 and its rapidly spreading variants. Several natural compounds show potential as antiviral substances and have the advantages of broad availabilities and large therapeutic windows. Here, we report that lectin from Triticum vulgaris (Wheat Germ Agglutinin) displays antiviral activity against SARS-CoV-2 and its major Variants of Concern (VoC), Alpha and Beta. In Vero B4 cells, WGA potently inhibits SARS-CoV-2 infection with an IC50 of |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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