Sideroxylonal C, a new inhibitor of human plasminogen activator inhibitor type-1, from the flowers of Eucalyptus albens

Autor: J, Neve, P A, Leone, A R, Carroll, R W, Moni, N J, Paczkowski, G, Pierens, P, Björquist, J, Deinum, J, Ehnebom, T, Inghardt, G, Guymer, P, Grimshaw, R J, Quinn
Rok vydání: 1999
Předmět:
Zdroj: Journal of natural products. 62(2)
ISSN: 0163-3864
Popis: Sideroxylonal C (3), a new phloroglucinol dimer, was isolated from the flowers of Eucalyptus albens through bioassay-guided fractionation. The structure elucidation was based on 1D and 2D NMR experiments, MS analysis, and comparison with sideroxylonals A (1) and B (2). Sideroxylonal C inhibited human plasminogen activator inhibitor type-1 at 4.7 microM without any significant effect on human tissue plasminogen activator.
Databáze: OpenAIRE