Hepatitis C virus serology in parenteral drug users with chronic liver disease

Autor:	D M, Novick, K J, Reagan, T S, Croxson, A M, Gelb, R J, Stenger, M J, Kreek
Rok vydání:	1997
Předmět:	Adult Liver Cirrhosis Male Alcoholism Chronic Disease Humans Female Hepatitis C Antibodies Substance Abuse Intravenous Hepatitis C
Zdroj:	Addiction (Abingdon, England). 92(2)
ISSN:	0965-2140
Popis:	Chronic liver disease is a common complication of parenteral drug use, and liver cirrhosis is frequently seen in users of both parenteral drugs and alcohol. In 1978-83, we studied 88 parenteral drug users with sufficient evidence of chronic liver disease to warrant liver biopsy. Current alcohol abuse was noted in 63 (72%), and six (7%) were former alcohol abusers. Cirrhosis was found in 33 (38%). Hepatitis C antibody (anti-HCV) was detected in 86 (98%). Also, 40 of the anti-HCV positive sera were tested with recombinant immunoblot assay and all of these were reactive. All but one of the 31 patients with anti-HCV and cirrhosis were alcohol abusers. We conclude that parenteral drug users with chronic liver disease almost always have evidence of HCV infection.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::cdc65c5ee5c88521979ce37cd05e2341 https://pubmed.ncbi.nlm.nih.gov/9158228 Zobrazit plný text záznamu Plný text ve formátu PDF Plný text ve formátu HTML
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