Antiinflammatory activity of alpha-methyl-3-phenyl-7-benzofuranacetic acid (R-803)

Autor:	K F, Swingle, R A, Scherrer, T J, Grant
Rok vydání:	1975
Předmět:	Male Radiation Injuries Experimental Granuloma Erythema Ultraviolet Rays Arthritis Guinea Pigs Anti-Inflammatory Agents Animals Edema Female Benzofurans Rats
Zdroj:	Archives internationales de pharmacodynamie et de therapie. 214(2)
ISSN:	0003-9780
Popis:	The antiinflammatory activity of R-803 (alpha-methyl-3-phenyl-7-benzofuranacetic acid), a new nonsteroidal drug, has been demonstrated. The oral administration of R-803 inhibits carrageenan-induced edema of the rat's paw, ultraviolet-induced erythema of guinea-pig skin, adjuvant-induced and 6-sulfonamidoindazole-induced arthritides of the rat at doses in the range of 1.0 to 6.0 mg/kg. It also inhibits the cotton pellet-induced granuloma in the rat at higher doses.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::cdb430174b37d921dae40eab29cebbc8 https://pubmed.ncbi.nlm.nih.gov/1156032 Zobrazit plný text záznamu