| Autor: |
A B, Bahnson, M, Nimgaonkar, E D, Ball, J A, Barranger |
| Rok vydání: |
2014 |
| Zdroj: |
Methods in molecular medicine. 7 |
| ISSN: |
1543-1894 |
| Popis: |
Hematopoietic stem cells (HSC) provide for contmuous replenishment of the entire immune and hematopoietic systems, and also replenish themselves in a process termed self-renewal (1).The HSCs can be enriched from hematopoietic tissues using MAbs that bind to the CD34 antigen, a universally recognized marker for hematopoietic progenitors (2-4).Enriched HSC populations are being widely investigated for use in transplantation and gene therapy because they appear to provide rapid hematopoietic reconstitution in myeloablated patients (5-11), and they offer good targets for gene transfer (12-17). |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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