[Modification of adrenergic regulation of heart function under effect of radio-ecological factors within 10-kilometer zone of the accident at Chernobyl nuclear plant]

Autor: L M, Lobanok, A E, Kirienkov, N V, Gerasimovich
Rok vydání: 1993
Předmět:
Zdroj: Radiatsionnaia biologiia, radioecologiia. 33(4)
ISSN: 0869-8031
Popis: Rats kept within the ten-kilometer zone of Chernobyl disaster over a period of 30 days exhibited a decreased heart function response to beta-adrenoreceptor stimulus, reduced density of the receptor structures in cardiomyocytes and their affinity to specific agonists. The number of beta-adrenoreceptors in myocardium cells was restored in 6 months, but their affinity and heart function response to the effect of beta-adrenoagonists remained decreased. No significant changes were observed in regulation influenced indirectly via alpha-adrenoreceptors.
Databáze: OpenAIRE