Chromatographic method for clobetasol propionate determination in hair follicles and in different skin layers

Autor:	Tamara, Ângelo, Marcílio S S, Cunha-Filho, Guilherme M, Gelfuso, Tais, Gratieri
Rok vydání:	2016
Předmět:	Chromatography Reverse-Phase Clobetasol Limit of Detection Skin Absorption Anti-Inflammatory Agents Humans Glucocorticoids Hair Follicle Chromatography High Pressure Liquid Skin
Zdroj:	Biomedical chromatography : BMC. 31(2)
ISSN:	1099-0801
Popis:	Clobetasol propionate (CLO) is a potent steroid used for the treatment of several dermatological diseases. Recent studies suggest its additional use in alopecia topical treatment, generating a demand for novel formulations with specific delivery into hair follicles. Hence, a selective analytical method for drug quantification in follicular structures and skin layers is required. For this, a simple HPLC-UV method was developed. Quantification was performed using a RP-C
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::cd426aa031a1dffc6ee5f3b33fed95b3 https://pubmed.ncbi.nlm.nih.gov/27502902 Zobrazit plný text záznamu Plný text