| Autor: |
Syed Imran, Ali, Nighat, Razvi, Syed Mohammad Farid, Hasan |
| Rok vydání: |
2018 |
| Předmět: |
|
| Zdroj: |
Pakistan journal of pharmaceutical sciences. 31(4(Supplementary)) |
| ISSN: |
1011-601X |
| Popis: |
Pioglitazone is widely used for the management of type-II diabetes mellitus. The objective of the present study was to develop a simple and cost-effective HPLC method for the quantification of pioglitazone in human plasma. The mobile phase comprises of Acetonitrile, 0.1 M ammonium acetate and glacial acetic acid (25:25:1 v/v/v) at a flow rate of 1.2 mL/min., using Macherey-Nagel Column C18, (dimensions: 5 μm; 250 × 4.6mm) with a guard column. The UV detector was set at 269nm. The method was validated according to FDA guidelines. The present method showed good linearity (R |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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