Impaired Intracellular Ca
| Autor: | Enrico, Pierantozzi, Péter, Szentesi, Cecilia, Paolini, Beatrix, Dienes, János, Fodor, Tamás, Oláh, Barbara, Colombini, Dilson E, Rassier, Egidio Maria, Rubino, Stephan, Lange, Daniela, Rossi, László, Csernoch, Maria Angela, Bagni, Carlo, Reggiani, Vincenzo, Sorrentino |
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| Rok vydání: | 2021 |
| Předmět: |
Ankyrins
Male Mice Knockout Sarcomeres Muscle Fibers Skeletal Muscle Proteins Protein Serine-Threonine Kinases Sarcoplasmic Reticulum Calcium-Transporting ATPases Mice Sarcoplasmic Reticulum Physical Conditioning Animal Animals Calcium Connectin Muscle Skeletal Rho Guanine Nucleotide Exchange Factors Muscle Contraction |
| Zdroj: | International journal of molecular sciences. 23(3) |
| ISSN: | 1422-0067 |
| Popis: | Obscurin is a giant sarcomeric protein expressed in striated muscles known to establish several interactions with other proteins of the sarcomere, but also with proteins of the sarcoplasmic reticulum and costameres. Here, we report experiments aiming to better understand the contribution of obscurin to skeletal muscle fibers, starting with a detailed characterization of the diaphragm muscle function, which we previously reported to be the most affected muscle in obscurin ( |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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