| Autor: |
Sook-Yee, Yoon, Siu Wan, Wong, Joanna, Lim, Syuhada, Ahmad, Shivaani, Mariapun, Heamanthaa, Padmanabhan, Nur Tiara, Hassan, Shao Yan, Lau, Gaik-Siew, Ch'ng, Muzhirah, Haniffa, Winnie P, Ong, Kavitha, Rethanavelu, Lip Hen, Moey, Wee Teik, Keng, Jamil, Omar, Mohd Norazam, Mohd Abas, Chee Meng, Yong, Vickneswaren, Ramasamy, Mohd Rushdan, Md Noor, Ismail, Aliyas, Michael C K, Lim, Anuradha, Suberamaniam, Noor Azmi, Mat Adenan, Zatul Akmar, Ahmad, Gwo Fuang, Ho, Rozita, Abdul Malik, Suguna, Subramaniam, Boom Ping, Khoo, Arivendran, Raja, Yeung Sing, Chin, Wee Wee, Sim, Beng Hock, Teh, Swee Kiong, Kho, Eunice S E, Ong, Pei Jye, Voon, Ghazali, Ismail, Chui Ling, Lee, Badrul Zaman, Abdullah, Kwong Sheng, Loo, Chun Sen, Lim, Saw Joo, Lee, Keng Joo Lim, Lim, Mohamad Nasir, Shafiee, Fuad, Ismail, Zarina Abdul, Latiff, Mohd Pazudin, Ismail, Mohamad Faiz, Mohamed Jamli, Suresh, Kumarasamy, Kin Wah, Leong, John, Low, Mastura, Md Yusof, Ahmad Muzamir, Ahmad Mustafa, Nor Huda, Mat Ali, Mary, Makanjang, Shahila, Tayib, Nellie, Cheah, Boon Kiong, Lim, Chee Kin, Fong, Yoke Ching, Foo, Matin, Mellor Abdullah, Teck Sin, Tan, Doris S Y, Chow, Kean Fatt, Ho, Rakesh, Raman, Ahmad, Radzi, Azura, Deniel, Daren C Y, Teoh, Soo Fan, Ang, Joseph K, Joseph, Paul Hock Oon, Ng, Lye-Mun, Tho, Azura Rozila, Ahmad, Ileena, Muin, Eveline, Bleiker, Angela, George, Meow-Keong, Thong, Yin Ling, Woo, Soo Hwang, Teo |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Journal of medical genetics. 59(3) |
| ISSN: |
1468-6244 |
| Popis: |
Identifying patients withThe Mainstreaming Genetic Counselling for Ovarian Cancer Patients (MaGiC) study is a prospective, two-arm observational study comparing oncologist-led and genetics-led counselling. This study included 790 multiethnic patients with ovarian cancer from 23 sites in Malaysia. We compared the impact of different method of delivery of genetic counselling on the uptake of genetic testing and assessed the feasibility, knowledge and satisfaction of patients with ovarian cancer.Oncologists were satisfied with the mainstreaming experience, with 95% indicating a desire to incorporate testing into their clinical practice. The uptake of genetic testing was similar in the mainstreaming and genetics arm (80% and 79%, respectively). Patient satisfaction was high, whereas decision conflict and psychological impact were low in both arms of the study. Notably, decisional conflict, although lower than threshold, was higher for the mainstreaming group compared with the genetics arm. Overall, 13.5% of patients had a pathogenic variant inThe MaGiC study demonstrates that mainstreaming cancer genetics is feasible in low-resource and middle-resource Asian setting and increased coverage for genetic testing. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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