| Autor: |
E V, Kudriavtseva, M V, Sidorova, M V, Ovchinnikov, Zh D, Bespalova, V N, Bushuev, R P, Evstigneeva |
| Rok vydání: |
1996 |
| Předmět: |
|
| Zdroj: |
Bioorganicheskaia khimiia. 22(5) |
| ISSN: |
0132-3423 |
| Popis: |
Removal of Acm-protecting group from thiol functional groups of Cys residues with simultaneous disulfide bridge formation by iodine in acetic acid was studied in the course of the synthesis of a peptide fragment corresponding to 593-603 sequence of HIV-2 gp41 glycoprotein. The excess iodine influence on the cyclization process was investigated. By-products of the oxidative disulfide formation were isolated, and their structures were elucidated by means of amino acid and elemental analyses, mass spectrometry, NMR, and UV-spectroscopy. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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