| Autor: |
N M, Anichkov, I I, Lomakina, Iu N, Zubzhitskiĭ |
| Rok vydání: |
1980 |
| Předmět: |
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| Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny. 89(6) |
| ISSN: |
0365-9615 |
| Popis: |
Administration of complete Freund's adjuvant (CFA) to rats before carcinogenesis and in its early period was associated with an increase (not less than 2-fold) in the number of spindle-shaped dark cells that permeated the hyperplastic urothelium and, judging the ultrastructure, had a macrophage nature. These animals demonstrated a relationship between the increased number of dark cells and delayed development of the subsequent stage of carcinogenesis--papillomatous hyperplasia. CFA administration to the animals with a developed cancer of the urinary bladder did not affect it noticeably. It did not produce any effect on subcutaneous transplantation of cancer that had taken in 100% of cases. No morphological features of carcinogenesis were recorded either after levamisol administration. However, none of the tumours withdrawn from the rats given levamisol took under the skin of the recipients. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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