Design and Synthesis of Protein-Based Nanocapsule Vaccines

Autor: Ivana, Skakic, Jasmine E, Francis, Peter M, Smooker
Rok vydání: 2021
Předmět:
Zdroj: Methods in molecular biology (Clifton, N.J.). 2412
ISSN: 1940-6029
Popis: Increasing emergence of infectious diseases is driving demand for new vaccine technologies capable of improving antigen delivery and protective efficacy. Nanoparticle technology is a modern approach to antigen delivery, capable of stabilizing and increasing the amount of antigen delivered to immune cells. Protein-based nanoparticles are a biodegradable alternative to existing nanomaterials, offering a versatile and biocompatible approach to nanoparticle vaccine delivery. In this chapter, the methods for the synthesis and characterization of protein-based nanocapsule vaccines are discussed. Initially, the requirements for a suitable nanoparticle vaccine are outlined, and finally, methods for the design and synthesis of protein-based nanocapsule vaccines are explained.
Databáze: OpenAIRE