Effect of oligomannoside-type glycopeptides in diarrheal disease of rabbits induced by Escherichia coli strain RDEC-1

Autor:	P, Sherman, R, Soni, S, Del Vedovo, J R, Neeser
Rok vydání:	1989
Předmět:	Diarrhea Feces Carbohydrate Sequence Microvilli Culture Techniques Guinea Pigs Glycopeptides Animals Oligosaccharides Rabbits Bacterial Adhesion Escherichia coli Infections
Zdroj:	FEMS microbiology letters. 52(1-2)
ISSN:	0378-1097
Popis:	We examined the effects of a soluble receptor-like complex carbohydrate (an oligomannoside-type glycopeptide) on adherence of a type 1 fimbriated rabbit enteropathogen, Escherichia coli strain RDEC-1. Oligomannoside-type glycopeptide, but not a non-glycosylated peptide mixture used as control, inhibited adherence of type 1 fimbriated RDEC-1 to both rabbit ileal brush borders and guinea pig erythrocytes in vitro. In contrast, during RDEC-1 infection of rabbits the receptor-like oligomannoside did not affect the presence and severity of diarrhea, fecal shedding of organisms, luminal colonization by RDEC-1, or enteroadherence of organisms.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::cc4a4c331e033cbfaf35a74bcef864a8 https://pubmed.ncbi.nlm.nih.gov/2689275 Zobrazit plný text záznamu Plný text