[Prognostic significance of cell proliferation, microvascular density and androgen receptor level in prostatic adenocarcinoma]

Autor:	S I, Lefterov, S I, Gorelov, Iu A, Krivolapov
Rok vydání:	2010
Předmět:	Aged 80 and over Male Neovascularization Pathologic Microcirculation Prostatic Neoplasms Adenocarcinoma Middle Aged Prognosis Ki-67 Antigen Predictive Value of Tests Receptors Androgen Humans Aged Cell Proliferation
Zdroj:	Voprosy onkologii. 55(6)
ISSN:	0507-3758
Popis:	Our study was concerned with prognostic significance of immunophenotypical features of prostate adenocarcinoma such as Ki-67 proliferation, androgen receptors (AR), microvascular density (MVD) in the stroma and tumor glands. Ki-67, AR and MVD expression correlated inversely with PSA level during hormonotherapy (r=0.24-0.39) as well as tumor cell differentiation grade (r=0.23-0.25). High expression of the said markers involved reduced efficiency of hormonotherapy.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::cbfdea0ac4f5d7ef8902466e170ef08d https://pubmed.ncbi.nlm.nih.gov/20210018 Zobrazit plný text záznamu