Adequacy of nutritional support using computed tomography (CT) in patients with head and neck cancer (HNC) during chemo-radiotherapy (CRT)

Autor: Lorena, Arribas, Aida, Sabaté-Llobera, Miren, Taberna, Natalia, Pallarés, Alicia, Narro Marin, Nuria, Virgili, Laura, Hurtós, Inmaculada, Peiró, Esther, Vilajosana, Alicia, Lozano, Vickie, Baracos, Ricard, Mesia
Rok vydání: 2020
Předmět:
Zdroj: European journal of clinical nutrition. 75(10)
ISSN: 1476-5640
Popis: We assessed forty HNC patients receiving treatment with curative intent. Specific quantitative muscle and fat changes were evaluated using CT. Nutrition support was provided according to ESPEN guidelines, with adjusted body weight (ABW) in overweight/obese patients used to define their nutritional targets. Linear regression models were used to evaluate clinical predictors of tissue loss. Mean overall losses were body weight (-10.5%), and CT-defined muscle (-8.4%) and fat mass (-24.8%), p 0.001. A subset of 20 patients had high muscle loss (-14.7%) with concurrent negative energy balance as reflected by considerable fat loss (-29.7%); those tended to have higher baseline body mass index (26.2 vs. 23.3 kg/m
Databáze: OpenAIRE