Cellular and viral ligands that interact with the EGF receptor

Autor: G J, Todaro, T M, Rose, C E, Spooner, M, Shoyab, G D, Plowman
Rok vydání: 1990
Předmět:
Zdroj: Seminars in cancer biology. 1(4)
ISSN: 1044-579X
Popis: The growth regulatory functions of a family of structurally related polypeptides are mediated through the membrane-bound epidermal growth factor receptor molecule. This ligand family includes epidermal growth factor, transforming growth factor-alpha, amphiregulin, and polypeptides encoded by several poxviruses. The structural and functional properties that are characteristic of the ligand family provide a basis for possible evolutionary relationships among the various ligands.
Databáze: OpenAIRE