Doppler‐Derived Renal Venous Stasis Index in the Prognosis of Right Heart Failure
| Autor: | Husain‐Syed, Faeq, Birk, Horst‐Walter, Ronco, Claudio, Schörmann, Tanja, Tello, Khodr, Richter, Manuel J., Wilhelm, Jochen, Sommer, Natascha, Steyerberg, Ewout, Bauer, Pascal, Walmrath, Hans‐Dieter, Seeger, Werner, McCullough, Peter A., Gall, Henning, Ghofrani, H. Ardeschir |
|---|---|
| Jazyk: | angličtina |
| Rok vydání: | 2019 |
| Předmět: |
Heart Failure
Aged 80 and over Male Cardiorenal Syndrome Hypertension Pulmonary intrarenal venous flow patterns Ultrasonography Doppler venous congestion Middle Aged renal Doppler ultrasonography Prognosis Renal Veins cardiorenal syndromes pulmonary hypertension Humans Female Prospective Studies Vascular Diseases Original Research Aged |
| Zdroj: | Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease |
| ISSN: | 2047-9980 |
| Popis: | Background Persistent congestion with deteriorating renal function is an important cause of adverse outcomes in heart failure. We aimed to characterize new approaches to evaluate renal congestion using Doppler ultrasonography. Methods and Results We enrolled 205 patients with suspected or prediagnosed pulmonary hypertension (PH) undergoing right heart catheterization. Patients underwent renal Doppler ultrasonography and assessment of invasive cardiopulmonary hemodynamics, echocardiography, renal function, intra‐abdominal pressure, and neurohormones and hydration status. Four spectral Doppler intrarenal venous flow patterns and a novel renal venous stasis index (RVSI) were defined. We evaluated PH‐related morbidity using the Cox proportional hazards model for the composite end point of PH progression (hospitalization for worsening PH, lung transplantation, or PH‐specific therapy escalation) and all‐cause mortality for 1‐year after discharge. The prognostic utility of RVSI and intrarenal venous flow patterns was compared using receiver operating characteristic curves. RVSI increased in a graded fashion across increasing severity of intrarenal venous flow patterns (P |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Plný text