| Popis: |
In normally fed lambs (group 1) the content of ascorbic acid (AA) in the plasma on day 8, 18, 28, 38, 48, 60 and 100 after birth was the same as in lambs, that were fed on days 8 to 17 (group 2), 8 to 26 (group 3) and 8 to 35 (group 4) on the maintenance level. The restrictive feeding induced for a certain time a decrease in the glucose content of the plasma. In the lambs of group 2 and 3 there was no differences in the content of AA in 14 tissues compared to group 1. In the lambs of group 4 the body weight on the 35th day was only 54 and the mass of the hypophysis 60, of the lung 55.9, of the liver 51, of the heart 47.2, of the spleen 44.7 and of the kidney 38% of that of group 1; there was a tendency to a lower content of AA in most tissues. With increasing age the content of AA in the cerebrum, in the cerebellum, in the brain stem and in the testicles decreased; the highest content in the hypophysis was determined on day 180. The regulation of the synthesis of AA in the liver under normal and pathological conditions is discussed. |
