Critical Closing Pressure During a Controlled Increase in Intracranial Pressure

Autor: Katarzyna, Kaczmarska, Magdalena, Kasprowicz, Antoni, Grzanka, Wojciech, Zabołotny, Peter, Smielewski, Despina Afroditi, Lalou, Georgios, Varsos, Marek, Czosnyka, Zofia, Czosnyka
Rok vydání: 2018
Předmět:
Zdroj: Acta neurochirurgica. Supplement. 126
ISSN: 0065-1419
Popis: The objectives were to compare three methods of estimating critical closing pressure (CrCP) in a scenario of a controlled increase in intracranial pressure (ICP) induced during an infusion test in patients with suspected normal pressure hydrocephalus (NPH).We retrospectively analyzed data from 37 NPH patients who underwent infusion tests. Computer recordings of directly measured intracranial pressure (ICP), arterial blood pressure (ABP) and transcranial Doppler cerebral blood flow velocity (CBFV) were used. The CrCP was calculated using three methods: first harmonics ratio of the pulse waveforms of ABP and CBFV (CrCPThere is good agreement among the three methods of CrCP calculation, with correlation coefficients being greater than 0.8 (p0.0001). For the CrCPInvasive CrCP is most sensitive to variations in ICP and can be used as an indicator of the status of the cerebrovascular system during infusion tests.
Databáze: OpenAIRE