Antibody levels to Salmonella typhi and paratyphi in Nigerians
| Autor: | K B, Tanyigna, J A, Ayeni, E N, Okeke, J A, Onah, C S, Bello |
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| Rok vydání: | 2000 |
| Předmět: |
Adult
Aged 80 and over Male Adolescent Urban Health Nigeria Reproducibility of Results Middle Aged Salmonella typhi Antibodies Bacterial Age Distribution Cross-Sectional Studies Seroepidemiologic Studies Salmonella paratyphi A Surveys and Questionnaires Paratyphoid Fever Humans Female Serologic Tests Sex Distribution Typhoid Fever Child Aged |
| Zdroj: | East African medical journal. 76(11) |
| ISSN: | 0012-835X |
| Popis: | To determine the antibody titre levels to typhoid/paratyphoid fever organisms among apparently healthy volunteers.Cross sectional study.General community and University Teaching Hospital.Volunteer sample of 323 apparently healthy individuals with body temperaturesor = 37.8 degrees C.Questionnaire administration to classify volunteers into three socio-economic status (SES).There were 35.29% of the apparently healthy population in Jos community with antibodies to typhoid/paratyphoid fever organisms. The presence of these antibodies were neither sex nor SES related. Normal antibody titres were up to 1:40 and 1:80 for O and H Salmonella antigens respectively. Contrary to the general belief, typhoid/paratyphoid fevers have not affected virtually everybody in Nigeria. The difference between those without previous history and those with previous history was significant (p0.05) with those in the former category having a higher percentage.For a single sero-diagnosis to have any diagnostic value in Jos community and its environs, only a four-fold rise to what has been found to be normal should be significant. This means that only titres of 1:160 and 1:320 and above for O and H antigens should be considered significant. |
| Databáze: | OpenAIRE |
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