Effect of ceftazidime/avibactam plus fosfomycin combination on 30 day mortality in patients with bloodstream infections caused by KPC-producing

Autor: A, Oliva, L, Volpicelli, S, Di Bari, A, Curtolo, C, Borrazzo, F, Cogliati Dezza, A, Cona, S, Agrenzano, A, Mularoni, M, Trancassini, F, Mengoni, S, Stefani, G, Raponi, M, Venditti
Rok vydání: 2022
Zdroj: JAC-antimicrobial resistance. 4(6)
ISSN: 2632-1823
Popis: The primary outcome of the study was to evaluate the effect on 30 day mortality of the combination ceftazidime/avibactam + fosfomycin in the treatment of bloodstream infections (BSIs) caused by KPC-producingFrom October 2018 to March 2021, a retrospective, two-centre study was performed on patients with KPC-Overall, 221 patients were included in the study. Following the 1:1 match, 122 subjects were retrieved: 61 cases (ceftazidime/avibactam + fosfomycin) and 61 controls (ceftazidime/avibactam ± other). No difference in overall mortality emerged between cases and controls, whereas controls had more non-BSI KPC-Our data show that fosfomycin was used in the treatment of KPC
Databáze: OpenAIRE