| Autor: |
V V, Rozhanets, D Iu, Rusakov, N D, Danchev, A V, Val'dman |
| Rok vydání: |
1983 |
| Předmět: |
|
| Zdroj: |
Biulleten' eksperimental'noi biologii i meditsiny. 96(7) |
| ISSN: |
0365-9615 |
| Popis: |
A study was made of the effect of a two-week administration of chlorimipramine, zimelidine and a morpholine derivative on benzodiazepine receptors of the mouse brain. The animals which received antidepressants demonstrated a significant increase in the binding sites of 3H-flunitrazepam without any changes in the dissociation constant as compared to control. The data on the evoked aggressiveness and latency of tonic corasole convulsions in the antidepressant-treated animals support the functional importance of the discovered changes in benzodiazepine receptors. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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