Congenital dyserythropoietic anemia type II. Radioautographic, ultrastructural and cytogenetical study in two familial cases

Autor: A, Colită, C, Ursea, A, Jost, E, Butoianu, S T, Nicoara, G M, Grigoriu, S, Berceanu
Rok vydání: 1976
Předmět:
Zdroj: Medecine interne. 14(1)
ISSN: 0377-1202
Popis: The case of two sisters is reported in whom morphological (multinucleated erythroblasts in the bone marrow) and serological (positive Ham test, negative sucrose and water-sugar tests) characteristics of a congenital dyserythropoietic anemia type II were found. Radioautographic, cytogenetic and electron microscope studies confirmed the presence of an inefficient erythropoiesis and of a membrane defect, common in this disease. The finding of a nil LAP score has never been reported so far.
Databáze: OpenAIRE