THE ROLE OF BILE ACIDS IN THE REGULATION OF LIPID AND CARBOHYDRATE METABOLISM IN PATIENTS WITH NONALCOHOLIC FATTY LIVER DISEASE AND DIABETES TYPE2

Autor: L A, Zvenigorodskaya, A V, Petrakov, T V, Nilova, G G, Varvanina, A E, Lychkova
Rok vydání: 2018
Předmět:
Zdroj: Eksperimental'naia i klinicheskaia gastroenterologiia = Experimentalclinical gastroenterology. (11)
ISSN: 1682-8658
Popis: Bile acids regulate glucose and lipid metabolism. Aim -determination of total serum bile acids in patients with NAFLD and in combination with type 2 diabetes. To determine the inflammatory markers (nitric oxide, endotoxin, phospholipase A2, malondialdehyde) effects role for the synthesis and transport of bile acids. NAFLD patients with type 2 diabetes observed decrease in synthesis and disruption of transport of bile acids, which is associated with the cell membrane damage by inhibition of enzyme systems, and inflammation.
Databáze: OpenAIRE