| Autor: |
R P, González-Peralta, J M, Andres, F Y, Tung, J W, Fang, M E, Brunson, G L, Davis, J Y, Lau |
| Rok vydání: |
1994 |
| Předmět: |
|
| Zdroj: |
Transplantation. 58(1) |
| ISSN: |
0041-1337 |
| Popis: |
A critically ill, HBV seronegative girl who received a liver from a HBsAg+ donor is described. Despite HBV Ig prophylaxis, she was seropositive for HBsAg shortly after transplantation. Although the postoperative period was complicated, HBV-related problems were not encountered. Liver dysfunction was noted 7 months after transplantation. At that time, she became anti-HBc IgM-positive, with liver histologic findings suggestive of chronic active hepatitis B. The liver function normalized after a reduction of immunosuppressive therapy and introduction of ciprofloxacin. The patient had low level HBV replication during the entire follow-up period (HBV DNA-positive by PCR only) and sequencing of the virus on 4 occasions revealed only wild-type HBV. She subsequently lost serum HBsAg and HBV DNA (even by PCR) and has remained well 2 years after transplantation. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
|
