Prognostic significance of red blood cell distribution width in gastrointestinal cancers

Autor: Zhou, Yongping, Li, Xiding, Lu, Zhihua, Zhang, Lei, Dai, Tu
Jazyk: angličtina
Rok vydání: 2020
Předmět:
Zdroj: Medicine
ISSN: 1536-5964
0025-7974
Popis: Supplemental Digital Content is available in the text
Background: Many publications showed red blood cell distribution width (RDW) might associate with the prognosis of gastrointestinal (GI) cancers, however, the agreement has not been reached because of controversial results. This meta-analysis aimed to explore the prognostic value of RDW in GI cancers. Methods: Four common databases were comprehensively searched to look for relevant studies. The meta-analyses for overall survival (OS) and disease-free survival were performed using hazard ratio (HR) and 95% confidence interval (CI), and the meta-analyses for clinical parameters were conducted using odd ratio and 95% CI. Results: A total of 13 studies involving with 3,509 patients with GI cancers were included into this study. The results showed, compared to patients with low RDW, patients with high RDW tended to have shorter OS (HR = 1.75, 95%CI = 1.57–1.94, P
Databáze: OpenAIRE