Prenatal androgen exposure and transgenerational susceptibility to polycystic ovary syndrome

Autor:	Sanjiv, Risal, Yu, Pei, Haojiang, Lu, Maria, Manti, Romina, Fornes, Han-Pin, Pui, Zhiyi, Zhao, Julie, Massart, Claes, Ohlsson, Eva, Lindgren, Nicolas, Crisosto, Manuel, Maliqueo, Barbara, Echiburú, Amanda, Ladrón de Guevara, Teresa, Sir-Petermann, Henrik, Larsson, Mina A, Rosenqvist, Carolyn E, Cesta, Anna, Benrick, Qiaolin, Deng, Elisabet, Stener-Victorin
Rok vydání:	2019
Předmět:	Gene Expression Regulation Developmental Nuclear Family Cohort Studies Obesity Maternal Mice Phenotype Pregnancy Prenatal Exposure Delayed Effects Androgens Oocytes Animals Humans Female Single-Cell Analysis Polycystic Ovary Syndrome
Zdroj:	Nature medicine. 25(12)
ISSN:	1546-170X
Popis:	How obesity and elevated androgen levels in women with polycystic ovary syndrome (PCOS) affect their offspring is unclear. In a Swedish nationwide register-based cohort and a clinical case-control study from Chile, we found that daughters of mothers with PCOS were more likely to be diagnosed with PCOS. Furthermore, female mice (F
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=pmid________::c70a6eadaf96d03d93f34ee1a24be183 https://pubmed.ncbi.nlm.nih.gov/31873208 Zobrazit plný text záznamu Full text from SpringerLink