| Autor: |
Karen B, Poulsen, Marcell J, Tjørnild, Søren N, Skov, Mona, Sharghbin, Lisa Carlson, Hanse, Leila L, Benhassen, Diana M, Røpcke, Sten L, Nielsen, J Michael, Hasenkam |
| Rok vydání: |
2020 |
| Předmět: |
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| Zdroj: |
Cardiovascular engineering and technology. 11(6) |
| ISSN: |
1869-4098 |
| Popis: |
Patch reconstruction of the posterior mitral leaflet using small intestinal submucosa extracellular matrix has been successfully performed in a porcine study. The patch reconstruction, however, resulted in non-physiological systolic widening of the mitral annulus, suggesting the need for an annuloplasty ring. The objective was to characterize the impact on annular dynamics and leaflet geometry of adding a flexible annuloplasty ring to the posterior mitral leaflet patch reconstruction.Measurements were performed in an acute 80-kg porcine model, with seven pigs acting as their own controls. The posterior mitral leaflet was reconstructed with a 2-ply small intestinal submucosa extracellular matrix patch (CorMatrix®). Additionally, a Simulus® Flexible Annuloplasty Ring (Medtronic Inc., Minneapolis, MN, USA) was inserted. Mitral annular dynamics were evaluated using sonomicrometry, and leaflet geometry was described using echocardiography.The annuloplasty ring reduced mitral annular dimensions and restricted cyclic changes in mitral annular area (126 ± 19 vs. 30 ± 13 mmThe flexible annuloplasty ring resulted in a downsized annulus with restriction of cyclic annular changes in the reconstructed mitral valve. Ring insertion preserved the annular saddle shape and coaptation length. The ring annuloplasty counteracted the non-physiological annular dynamics, and this may improve durability of the posterior mitral leaflet patch reconstruction. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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