Inhibition of Quorum-Sensing Regulator from

Autor: Yanxuan, Xie, Jingxin, Chen, Bo, Wang, Ai-Yun, Peng, Zong-Wan, Mao, Wei, Xia
Rok vydání: 2022
Předmět:
Zdroj: Molecules (Basel, Switzerland). 27(8)
ISSN: 1420-3049
Popis: Quorum sensing (QS) is a cell-to-cell communication process that controls bacterial collective behaviors. The QS network regulates and coordinates bacterial virulence factor expression, antibiotic resistance and biofilm formation. Therefore, inhibition of the QS system is an effective strategy to suppress the bacterial virulence. Herein, we identify a phosphate ester derivative of chrysin as a potent QS inhibitor of the human pathogen
Databáze: OpenAIRE