| Autor: |
H, Fernandez, S, Pauthier, D, Sitbon, Y, Vincent, S, Doumerc |
| Jazyk: |
francouzština |
| Rok vydání: |
1996 |
| Předmět: |
|
| Zdroj: |
Contraception, fertilite, sexualite (1992). 24(4) |
| ISSN: |
1165-1083 |
| Popis: |
to compare methotrexate (MTX) to laparoscopic salpingotomy for conservative management of ectopic pregnancy (EP).prospective randomized study.eighty-nine patients were randomized into 2 groups using a random number table. Inclusion criteria were an EP visualized by ultrasound with a pretherapeutic scoreor = 13 as assessed by 6 criteria graded from 1 to 3: gestational age, hCG level, P level, abdominal pain, volume of the hemoperitoneum, and diameter of the hematosalpinx.1 mg/kg of MTX injected transvaginally into the ectopic pregnancy without anaesthesia or IM administration (1.5 mg/kg) when EP cannot be safely or easily punctured (group 1) versus laparoscopic salpingotomy (group 2).the success rates defined by hCG levels returned to normal (10 mlU/mL) were 43 out of 46 in group 1 and 40 out of 43 in group 2. Medical treatment was significantly associated with shorter post-operative stay (24 vs 46 hours). hCG return to normal was quicker after laparoscopic treatment (13 vs 29 days). Reproductive performances were similar in both groups.in selected cases of EP with a pretherapeutic scoreor = 13, MTX treatment appeared to be as safe and efficient as was conservative treatment by laparoscopy, an expectant management should be offered as a treatment option only in women fulfilling the criteria for a good prognostic. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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