| Autor: |
A G, Gubaev, E A, Ortenberg, O A, Rusakova, E A, Chiriat'ev |
| Rok vydání: |
1996 |
| Předmět: |
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| Zdroj: |
Eksperimental'naia i klinicheskaia farmakologiia. 59(1) |
| ISSN: |
0869-2092 |
| Popis: |
Nondialyzed fraction of the ammonia extract from Siberian grass Nonea poulla is studied. A stable hypocoagulemy (without cumulative activity) was found in the experiments in vitro and in vivo carried out on rats (intravenous administration of the extract). The LD50 was 150 mg/kg at the effective dose of 10 mg/kg. Intraperitoneal and intramuscular administration during 20 days exerted neither hypocoagulemic nor toxic effect on the haemopoesis system and did not change the body weight of the animals. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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