Autor: |
Yumiko, Ohbayashi, Osamu, Imataki, Ayuko, Higuchi, Minoru, Miyake, Yukiko, Ohue, Hiroaki, Ohnishi |
Rok vydání: |
2007 |
Předmět: |
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Zdroj: |
[Rinsho ketsueki] The Japanese journal of clinical hematology. 48(11) |
ISSN: |
0485-1439 |
Popis: |
The standard treatment for refractory oral chronic graft versus host disease (GVHD) has not been established. We present a case of AML accompanied by oral chronic GVHD in a 55-year-old man after allogeneic stem cell transplantation. The stomatitis of the patient was prolonged for a year and resistant to standard immunosuppressant therapy, including systemic administration of prednisolone and tacrolimus; however, local injection of 0.2% dexamethasone (0.5 mg per cm2) into the ulcerative area was drastically effective in improving refractory mucositis and mitigated a vicious cycle of mucosal damage and poor oral hygiene. |
Databáze: |
OpenAIRE |
Externí odkaz: |
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