[Changes in extracellular K+ concentration modulate properties of voltage dependent K+ channel conductance in PC-12 cells]

Autor: N Ia, Boĭko, V V, Kucher, N Kh, Pohoriela, I S, Mahura
Rok vydání: 2004
Předmět:
Zdroj: Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). 50(4)
ISSN: 2522-9028
Popis: The complex processing and integration of signals observed in neurons are facilitated by the diverse range of gating properties of the ion channels in this cell type, particularly the voltage-gated K+ channels (Kv). A distinctive combination of K+ channels endows neurons with a broad repertoire of excitable properties and allows each neuron to respond in a specific manner to a given input at a given time. The properties of many K+ channels can be modulated by second messenger pathways activated by neurotransmitters and other stimuli. K+ channels are among the most frequent targets of the actions of several signalling systems.
Databáze: OpenAIRE